- Analysis of musculo-skeletal loading during fracture healing and aging

- Biology of Fracture Healing

• Analysis of musculo-skeletal loading during fracture healing and aging
• Musculo-skeletal loading in dia- and epi-physeal fracture of the femur, tibia and humerus
• Material properties and structure of bone as a function of age
• Pre-operative, load optimised planning of fracture treatment in metaphyseal fracture of the femur and tibia
• Characterization of the influence of the operative approach on fracture healing
• Formulation of standards for the experimental testing of new implants or devices
• Establishment of a validated database on musculo-skeletal loading in healthy individuals: Loads and strains in long bones

• Characterization of the biological healing process in bone defect healing and healing of shaft fracture: Loading, biomechanical quality of the regenerate tissue, histology of callus formation
• Relating biological outcome to mechanical conditions from musculo-skeletal analysis and transfer of animal experimental findings to patient relevant situations
• Establishment of a database on the histology and histomorphometry in respect to the mechanical loading environment